RECURRENCE FREE SURVIVAL AND PATTERNS OF RECURRENCE IN SQUAMOUS CELL CARCINOMA OF ORAL CAVITY: AN INSTITUTIONAL PERSPECTIVE

Objective: To determine the recurrence-free survival (RFS) in patients with squamous cell carcinoma of oral cavity (OSCC) Methodology: It was a longitudinal study conducted on oncology who were diagnosed as having and treated our tertiary care hospital department medical oncology. Patients followed for evaluation disease recurrence. The Chi-square test used to see association between outcomes clinicopathological features tumor. Results: Of 97 patients, 85(87.62%) had no disease, however, 12(12.37%) residual/recurrent first post-treatment follow-up scans performed three months after completion curative treatment. Subsequent showed recurrence 87(89.69%) out which 52 (59.77%) loco-regional while 35(40.22%) combined systemic lung(n=18) being most common site distant metastasis. mean RFS 15 (IQR= 8, 26). lymph vascular invasion (LVI), perineural (PNI), positive margin, extranodal extension(ENE) significantly higher risk progressive primary treatment, follow up scans. relationships treatment LVI, PNI, margin ENE statistically significant (p<0.05). Conclusion: Our shows that there is frequency OSCC among extra nodal extension, perineural-invasion, margins. Clinical trials are required identify other poor prognostic factors need developing model risk-stratification such patients.